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To develop and commercialize T-3525770 (now RM-853) for the treatment of Prader-Willi Syndrome
April 2, 2018
By: Betsy Louda
Rhythm Pharmaceuticals has acquired exclusive, worldwide rights from Takeda to develop and commercialize T-3525770 (now RM-853). RM-853 is a potent, orally available ghrelin o-acyltransferase (GOAT) inhibitor currently in preclinical development for Prader-Willi Syndrome (PWS). PWS is a rare genetic disorder that results in hyperphagia and early-onset, life-threatening obesity, for which there are no approved therapeutic options. Ghrelin is an orexigenic peptide, secreted by...
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